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当前位置: 首页 > 产品中心 > Other_imaging > asuragen/QuantideX®NGS DNA热点21试剂盒/48/46108
商品详细asuragen/QuantideX®NGS DNA热点21试剂盒/48/46108
asuragen/QuantideX®NGS DNA热点21试剂盒/48/46108
asuragen/QuantideX®NGS DNA热点21试剂盒/48/46108
商品编号: 46108
品牌: asuragen
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 其它成像系统
公司分类: Other_imaging
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

QuantideX® NGS DNA Hotspot 21 Kit

The QuantideX® NGS DNA Hotspot 21 Kit (RUO) is a next generation sequencing (NGS) research tool that interrogates 46 hotspot regions (amplicons) within 21 genes that are commonly mutated in a number of solid and hematological malignancies.  The kit detects over 1,500 known variants, including single nucleotide variants (SNVs), insertions/deletions (indels), and structural rearrangements.  Leveraging our proprietary NGS-in-a-Box™ workflow and Sample-Aware™ bioinformatics quality control solutions, this kit provides a simple, robust, and reliable NGS assay for the routine investigation of these genomic variants.

Features & Benefits

The QuantideX NGS DNA Hotspot 21 Kit combines Asuragen’s unique NGS-in-a-Box™ solution with a streamlined testing workflow to enable unprecedented NGS workflow efficiency and high sensitivity at low input amounts from precious FFPE samples.

Reduced ComplexityAssay incorporates sample-to-data solutions in a unique NGS-in-a-Box™ configuration

  • Detects >1,500 variants from commonly mutated genomic regions across multiple tumor types
  • End-to-end kitted solution
  • Fully integrated data analysis pipeline

Optimized WorkflowProvides operational efficiencies to reduce testing costs, hands-on and total turnaround time

  • Reduced labor required for library preparation
  • Improved turnaround time enables higher throughput
  • Common workflow across portfolio streamlines training & implementation

Quality PerformanceHighly sensitive assay with integrated, Sample-Aware™ bioinformatics software and built-in quality checks to minimize erroneous results and sample failures

  • Highly sensitive detection of DNA-based variants
  • Low input (~20ng) of DNA from FFPE
  • Sample-Aware™ bioinformatics analysis and sample quality control

Product Description

Relevant ContentThe QuantideX NGS DNA Hotspot 21 Kit detects over 1,500 genomic variants as reported in the Catalogue of Somatic Mutations in Cancer (COSMIC) Database within 21 genes, representing approximately 80% of known variants within these targets.

Table 1: Mutation coverage of QuantideX NGS DNA Hotspot 21 Kit

Table 2: Clinical relevance of covered mutations

1NCCN Clinical Practice Guidelines*Includes gastric, pancreatic, glicomas, sarcomas, and other tumor types

A Fully Integrated WorkflowA unique NGS-in-a-Box™ configuration offers a simplified and fully integrated NGS workflow with cGMP-manufactured reagents, components and controls ready to use.

Includes:

  • An internal quality control kit to measure the absolute copy number of amplifiable DNA and reports PCR inhibition
  • Gene-specific PCR primers and Master Mix reagents
  • Dual-index barcodes for sample multiplexing
  • Library purification and quantification reagents
  • Integrated data analysis and reporting software (QuantideX NGS Reporter)

Rapid & EfficientAdopt and run NGS-based analysis with minimum investment of time and resources, regardless of NGS experience and infrastructure.

  • Fully integrated workflow reduces complexity and ensures reliable reagent quality
  • Push-button analysis & reporting makes bioinformatics easy and efficient, regardless of experience level
  • Integrated kit reduces overall workflow time

Performance Data

Highly Sensitive and Accurate Detection of DNA Mutations

QuantideX® NGS Reporter

Push-button analytics & reporting suite – Set-up-and-go workflow designed for easy installation and implementation, right out of the box.

Operates on a standard desktop computer – Install locally on a desktop computer using Windows® operating system.  No prior bioinformatics experience or large server environments required.

Comprehensive– Full bioinformatics and reporting of variants (SNVs, Indels), and standard QC metrics are automatically calculated.

Integrates Sample-Aware – Bioinformatics with integrated functional template copy number analysis dramatically reduces false-call rates.

Resources

Videos

Next-Generation Sequencing Within Your Reach: Implementation of an Actionable Mutation Panel for Molecular Oncology Testing

Posters

Analytical Validation Of The QuantideX® NGS DNA Hotspot 21 Kit, A Diagnostic NGS System for the Detection of Actionable Mutations in FFPE TumorsView full poster

A Machine-Learning Framework for Accurate Classification and Quantification of Oncogenic Variants Using the QuantideX® NGS DNA Hotspot 21 KitView full poster

A Simple and Versatile Next-Generation Sequencing Technology for Co-Detection of RNA Structural Variants and DNA Mutations in Lung CancerView full poster 

Ordering

Product NameNumber of ReactionsCatalog Number
QuantideX NGS DNA Hotspot 21 Kit*4846108

T 1.877.777.1874 | 512.681.5200 F 512.681.5202 E orders@asuragen.com

View Sales Contacts

*For Research Use Only. Not for use in Diagnostic procedures.

QuantideX® NGS DNA Hotspot 21 Kit

The QuantideX® NGS DNA Hotspot 21 Kit is an in vitro diagnostic, next-generation sequencing (NGS) panel for the detection of clinically relevant variants across a multitude of tumor types, including non-small cell lung cancer, colorectal cancer, and melanoma.  The kit screens for over 1,500 known genomic variants, including single nucleotide variants (SNVs), insertions/deletions (indels), and structural rearrangements, many of which are treatable with novel therapies, inform on patient management, or are the subject of further clinical evaluation.  Leveraging our proprietary NGS-in-a-Box™ workflow and Sample-Aware™ bioinformatics quality control solutions, the panel provides a robust and reliable NGS solution for the identification of clinically relevant targets you and your clinicians can trust.

Features & Benefits

The QuantideX NGS DNA Hotspot 21 Kit combines Asuragen’s unique NGS-in-a-Box™ solution with a streamlined testing workflow to enable unprecedented NGS workflow efficiency and high sensitivity at low input amounts from precious FFPE samples.

Reduced ComplexityAssay incorporates sample-to-data solutions in a unique NGS-in-a-Box™ configuration

  • Detects >1,500 variants from commonly mutated genomic regions across multiple tumor types
  • End-to-end kitted solution
  • Fully integrated data analysis pipeline

Optimized WorkflowProvides operational efficiencies to reduce testing costs, hands-on and total turnaround time

  • Reduced labor required for library preparation
  • Improved turnaround time enables higher throughput
  • Common workflow across portfolio streamlines training & implementation

Quality PerformanceHighly sensitive assay with integrated, Sample-Aware™ bioinformatics software and built-in quality checks to minimize erroneous results and sample failures

  • Highly sensitive detection of DNA-based variants
  • Low input (~20ng) of DNA from FFPE
  • Sample-Aware™ bioinformatics analysis and sample quality control

Product Description

Relevant ContentThe QuantideX NGS DNA Hotspot 21 Kit detects over 1,500 genomic variants as reported in the Catalogue of Somatic Mutations in Cancer (COSMIC) Database within 21 genes, representing approximately 80% of known variants within these targets.  Several of these variants are associated with approved therapies, while others are currently in trials to clarify their clinical significance.

Table 1: Mutation coverage of QuantideX NGS DNA Hotspot 21 Kit

Table 2: Clinical relevance of covered mutations

1NCCN Clinical Practice Guidelines*Includes gastric, pancreatic, glicomas, sarcomas, and other tumor types

A Fully Integrated WorkflowA unique NGS-in-a-Box™ configuration offers a simplified and fully integrated NGS workflow with cGMP-manufactured reagents, components and controls ready to use.

Includes:

  • An internal quality control kit to measure the absolute copy number of amplifiable DNA and reports PCR inhibition
  • Gene-specific PCR primers and Master Mix reagents
  • Dual-index barcodes for sample multiplexing
  • Library purification and quantification reagents
  • Integrated data analysis and reporting software (QuantideX NGS Reporter)

Rapid & EfficientAdopt and run NGS-based analysis with minimum investment of time and resources, regardless of NGS experience and infrastructure.

  • Fully integrated workflow reduces complexity and ensures reliable reagent quality
  • Push-button analysis & reporting makes bioinformatics easy and efficient, regardless of experience level
  • Integrated kit reduces overall workflow time

Performance Data

Highly Sensitive and Accurate Detection of DNA Mutations

QuantideX® NGS Reporter

Push-button analytics & reporting suite – Set-up-and-go workflow designed for easy installation and implementation, right out of the box.

Operates on a standard desktop computer – Install locally on a desktop computer using Windows® operating system.  No prior bioinformatics experience or large server environments required.

Comprehensive – Full bioinformatics and reporting of variants (SNVs, Indels) and standard QC metrics are automatically calculated.

Integrates Sample-Aware – bioinformatics with integrated functional template copy number analysis dramatically reduces false-call rates.

Resources

Videos

Next-Generation Sequencing Within Your Reach: Implementation of an Actionable Mutation Panel for Molecular Oncology Testing

Posters

Analytical Validation Of The QuantideX® NGS DNA Hotspot 21 Kit, A Diagnostic NGS System for the Detection of Actionable Mutations in FFPE TumorsView full poster

A Machine-Learning Framework for Accurate Classification and Quantification of Oncogenic Variants Using the QuantideX® NGS DNA Hotspot 21 KitView full poster

A Simple and Versatile Next-Generation Sequencing Technology for Co-Detection of RNA Structural Variants and DNA Mutations in Lung CancerView full poster 

Ordering

Product NameNumber of ReactionsCatalog Number
QuantideX NGS DNA Hotspot 21 Kit*4876044

T 1.877.777.1874 | 512.681.5200 F 512.681.5202 E orders@asuragen.com

View Sales Contacts

*For Research Use Only. Not for use in Diagnostic procedures.

品牌介绍
asuragen的QuantideX®qPCR BCR-ABL次要试剂盒(RUO)BCR-ABL血液癌细胞该QuantideX ® qPCR的BCR-ABL轻微套件(RUO)是临床研究工具,使超灵敏和精确的检测BCR-ABL1从全血标本轻微融合基因(e1a2)。在简单的工作流程和最佳的一流的灵敏度与确立的全面建设FDA批准QuantideX ® qPCR的BCR-ABL IS套装,小工具允许实验室和临床研究人员研究疾病的生物学这一非常罕见的,但不同白血病变异与前所未有的轻松。特点与优势分析特性订购方式特点与优势QuantideX qPCR BCR-ABL次要试剂盒(RUO)通过无与伦比的灵敏度和优化的实验室效率提供了高性能。降低复杂性易于数据分析和报告:充分利用了QuantideX ® qPCR的BCR-ABL IS套装的工作流程概念简化实施随附的软件可自动计算BCR-ABL1 / ABL1%比率,无需手动计算优化的工作流程通过以下方式大大减少了宝贵的操作员动手时间:多重设计可在同一反应中扩增并检测融合基因和对照基因单一供应商共同采购和控制质量的全包试剂预混试剂可减少预混液的移液步骤通过高灵敏度的检测方法可靠,可靠地检测 BCR-ABL1次要转录本的质量表现:超灵敏的检测下限(LOD):对数减少4.61(比率为0.0025%)在不影响分析特异性的情况下提高分析灵敏度:结合了空白限度(LOB)以防止误判非白血病低阳性基于铠装RNA®的标准品可提供真正的RNA定量