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商品详细asuragen/QuantideX®NGS RNA肺癌试剂盒/192/49603
asuragen/QuantideX®NGS RNA肺癌试剂盒/192/49603
asuragen/QuantideX®NGS RNA肺癌试剂盒/192/49603
商品编号: 49603
品牌: asuragen
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 固醇类
公司分类: Sterols
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

QuantideX® NGS RNA Lung Cancer Kit

rna-lung-cancer-kit-box-photo-for-webThe QuantideX® NGS RNA Lung Cancer Kit* is a clinical research tool enabling the simultaneous assessment of fusions, exon skipping, and other expression targets frequently observed in non-small cell lung cancer (NSCLC). Leveraging our proprietary NGS-in-a-Box™ workflow and Sample-Aware™ bioinformatics quality control solutions, this kit offers a simple, sensitive, and reliable NGS assay for routine investigation of NSCLC samples.

Features & Benefits

The QuantideX NGS RNA Lung Cancer Kit offers a unique NGS-in-a-Box™ solution that provides unprecedented NGS workflow efficiency and high sensitivity at low input amounts from precious FFPE NSCLC samples.

Reduced ComplexityAssay incorporates sample-to-data solutions in a unique NGS-in-a-Box™ configuration

  • Single assay for a broad range of important NSCLC fusion targets
  • All-inclusive reagents from reverse transcription to NGS-ready library
  • Fully integrated data analysis pipeline

Optimized WorkflowEfficient workflow leads to lower operational costs and reduced hands-on and total turnaround time*

  • Reduced labor vs. current commercially available kits
  • Improved turnaround time enables higher throughput

*Internal data on file.

Quality PerformanceHighly sensitive assay with integrated, Sample-Aware™ bioinformatics software and built-in quality checks to minimize erroneous results and sample failures

  • Highly sensitive detection of RNA-based fusions
  • Low input (~20ng) of RNA from FFPE
  • Sample-Aware™ bioinformatics analysis and sample quality control

Download Brochure

*For Research Use Only. Not for use in Diagnostic procedures.

Product Description

Relevant ContentA focus on only the most important lung cancer fusion genes, MET exon 14 skipping events, 3’/5′ imbalances and mRNA expression from multiple published data sources such as COSMIC, ClinicalTrials.gov, NCCN Guidelines, etc.

  • 107 NSCLC-relevant fusions
  • ALK, RET, ROS1, and NTRK1 3’/5’ imbalances
  • MET exon 14 skipping events (e13/e14; e14/e15; e13/e15)
  • 23 mRNA targets, plus 3 endogenous control transcripts

A Fully Integrated WorkflowA unique NGS-in-a-Box™ configuration offers a simplified and fully integrated NGS workflow with cGMP-manufactured reagents, components and controls ready to run right out of the box.

Includes:

  • RT-PCR reagents
  • A unique RNA Lung Cancer Sample QC kit (QuantideX qPCR RNA Assay (Lung))
  • Gene-specific PCR primers and Master Mix reagents
  • Barcodes for sample multiplexing
  • Library purification and quantification reagents
  • Integrated data analysis and reporting software (QuantideX NGS Reporter)

workflow-image-for-web

Rapid & EfficientAdopt and run NGS-based analysis with minimum investment of time and resources, regardless of NGS experience and infrastructure.

  • Fully integrated workflow reduces complexity and ensures reliable reagent quality
  • Push-button analysis & reporting makes bioinformatics easy and efficient, regardless of experience level
  • Integrated kit reduces workflow time by over 50% than competing NGS panels

workflowanalyis_comparew-archer_updated

Performance DataQuantideX NGS Assay is capable of detecting fusions and splice variants down to 1:100 cells. (a) Admixture of MET exon 14 positive cell line in the background of wild-type cells, and (b) fusion, and (c) 3’/5’ imbalance status for an admixture of EML4-ALK positive FFPE in the background of a negative FFPE.

Figure 3a

Figure 3a

Figure 3b

Figure 3c

Figure 3c

*For Research Use Only. Not for use in Diagnostic procedures.

QuantideX® NGS Reporter

Quantidex-Reporter-ComputerPush-button analytics & reporting suite – Set-up-and-go workflow designed for easy installation and implementation, right out of the box.

Runs directly on lab desktop – Install locally on a Windows® desktop computer. No prior bioinformatics experience or large server environments required.

Comprehensive reporting – Full bioinformatics and reporting of variants (SNVs, SNPs, Indels, fusions), and standard QC metrics are automatically calculated.

Integrates QuantideX RNA/DNA QC AssaySample-Aware™ bioinformatics with integrated functional template copy number analysis dramatically reduces false-call rates.

Seamless updates offered with new panel designs & variant annotation – Software updates allow new panels to be adopted without re-investing in analytics when the Asuragen QuantideX NGS product line is adopted.

Contact us to request the QuantideX Reporter

Resources

Videos

Evaluation of an NGS Assay for Detecting RNA Fusions and Splicing Events in Lung Cancer

Next-Generation Sequencing Within Your Reach: Targeted RNA Sequencing to Help Guide NSCLC Patient Care

Posters

Accurate and Reproducible Detection of Fusions and Exon Skipping Events in NSCLC-Derived Samples Using A Comprehensive, Targeted RNA-Seq System Across Multiple LaboratoriesView full poster

Head-To-Head Comparison of Two Commercially Available Next-Generation Sequencing Technologies That Detect Gene Fusions In Non-Small Cell Lung CancerView full poster

A Simple and Versatile Next-Generation Sequencing Technology for Co-Detection of RNA Structural Variants and DNA Mutations in Lung Cancer View full poster

Ordering

Product NameNumber of ReactionsCatalog Number
QuantideX NGS RNA Lung Cancer Kit*4849602
QuantideX NGS RNA Lung Cancer Kit*19249603

T 1-877-777-1874; 512-681-5200 F 512-681-5202 E orders@asuragen.com

View Sales Contacts

*For Research Use Only. Not for use in Diagnostic procedures.

QuantideX® NGS RNA Lung Cancer Kit

rna-lung-cancer-kit-box-photo-for-webThe QuantideX® NGS RNA Lung Cancer Kit* is a clinical research tool enabling the simultaneous assessment of fusions, exon skipping, and other expression targets frequently observed in non-small cell lung cancer (NSCLC). Leveraging our proprietary NGS-in-a-Box™ workflow and Sample-Aware™ bioinformatics quality control solutions, this kit offers a simple, sensitive, and reliable NGS assay for routine investigation of NSCLC samples.

Features & Benefits

The QuantideX NGS RNA Lung Cancer Kit offers a unique NGS-in-a-Box™ solution that provides unprecedented NGS workflow efficiency and high sensitivity at low input amounts from precious FFPE NSCLC samples.

Reduced ComplexityAssay incorporates sample-to-data solutions in a unique NGS-in-a-Box™ configuration

  • Single assay for a broad range of important NSCLC fusion targets
  • All-inclusive reagents from reverse transcription to NGS-ready library
  • Fully integrated data analysis pipeline

Optimized WorkflowEfficient workflow leads to lower operational costs and reduced hands-on and total turnaround time*

  • Reduced labor vs. current commercially available kits
  • Improved turnaround time enables higher throughput

*Internal data on file.

Quality PerformanceHighly sensitive assay with integrated, Sample-Aware™ bioinformatics software and built-in quality checks to minimize erroneous results and sample failures

  • Highly sensitive detection of RNA-based fusions
  • Low input (~20ng) of RNA from FFPE
  • Sample-Aware™ bioinformatics analysis and sample quality control

Download Brochure

*For Research Use Only. Not for use in Diagnostic procedures.

Product Description

Relevant ContentA focus on only the most important lung cancer fusion genes, MET exon 14 skipping events, 3’/5′ imbalances and mRNA expression from multiple published data sources such as COSMIC, ClinicalTrials.gov, NCCN Guidelines, etc.

  • 107 NSCLC-relevant fusions
  • ALK, RET, ROS1, and NTRK1 3’/5’ imbalances
  • MET exon 14 skipping events (e13/e14; e14/e15; e13/e15)
  • 23 mRNA targets, plus 3 endogenous control transcripts

A Fully Integrated WorkflowA unique NGS-in-a-Box™ configuration offers a simplified and fully integrated NGS workflow with cGMP-manufactured reagents, components and controls ready to run right out of the box.

Includes:

  • RT-PCR reagents
  • A unique RNA Lung Cancer Sample QC kit (QuantideX qPCR RNA Assay (Lung))
  • Gene-specific PCR primers and Master Mix reagents
  • Barcodes for sample multiplexing
  • Library purification and quantification reagents
  • Integrated data analysis and reporting software (QuantideX NGS Reporter)

workflow-image-for-web

Rapid & EfficientAdopt and run NGS-based analysis with minimum investment of time and resources, regardless of NGS experience and infrastructure.

  • Fully integrated workflow reduces complexity and ensures reliable reagent quality
  • Push-button analysis & reporting makes bioinformatics easy and efficient, regardless of experience level
  • Integrated kit reduces workflow time by over 50% than competing NGS panels

workflowanalyis_comparew-archer_updated

Performance DataQuantideX NGS Assay is capable of detecting fusions and splice variants down to 1:100 cells. (a) Admixture of MET exon 14 positive cell line in the background of wild-type cells, and (b) fusion, and (c) 3’/5’ imbalance status for an admixture of EML4-ALK positive FFPE in the background of a negative FFPE.

Figure 3a

Figure 3a

Figure 3b

Figure 3c

Figure 3c

*For Research Use Only. Not for use in Diagnostic procedures.

QuantideX® NGS Reporter

Quantidex-Reporter-ComputerPush-button analytics & reporting suite – Set-up-and-go workflow designed for easy installation and implementation, right out of the box.

Runs directly on lab desktop – Install locally on a Windows® desktop computer. No prior bioinformatics experience or large server environments required.

Comprehensive reporting – Full bioinformatics and reporting of variants (SNVs, SNPs, Indels, fusions), and standard QC metrics are automatically calculated.

Integrates QuantideX RNA/DNA QC AssaySample-Aware™ bioinformatics with integrated functional template copy number analysis dramatically reduces false-call rates.

Seamless updates offered with new panel designs & variant annotation – Software updates allow new panels to be adopted without re-investing in analytics when the Asuragen QuantideX NGS product line is adopted.

Contact us to request the QuantideX Reporter

Resources

Videos

Evaluation of an NGS Assay for Detecting RNA Fusions and Splicing Events in Lung Cancer

Next-Generation Sequencing Within Your Reach: Targeted RNA Sequencing to Help Guide NSCLC Patient Care

Posters

Accurate and Reproducible Detection of Fusions and Exon Skipping Events in NSCLC-Derived Samples Using A Comprehensive, Targeted RNA-Seq System Across Multiple LaboratoriesView full poster

Head-To-Head Comparison of Two Commercially Available Next-Generation Sequencing Technologies That Detect Gene Fusions In Non-Small Cell Lung CancerView full poster

A Simple and Versatile Next-Generation Sequencing Technology for Co-Detection of RNA Structural Variants and DNA Mutations in Lung Cancer View full poster

Ordering

Product NameNumber of ReactionsCatalog Number
QuantideX NGS RNA Lung Cancer Kit*4849602
QuantideX NGS RNA Lung Cancer Kit*19249603

T 1-877-777-1874; 1-512-681-5200 F 1-512-681-5202 E orders@asuragen.com

View Sales Contacts

*For Research Use Only. Not for use in Diagnostic procedures.

品牌介绍
asuragen的QuantideX®qPCR BCR-ABL次要试剂盒(RUO)BCR-ABL血液癌细胞该QuantideX ® qPCR的BCR-ABL轻微套件(RUO)是临床研究工具,使超灵敏和精确的检测BCR-ABL1从全血标本轻微融合基因(e1a2)。在简单的工作流程和最佳的一流的灵敏度与确立的全面建设FDA批准QuantideX ® qPCR的BCR-ABL IS套装,小工具允许实验室和临床研究人员研究疾病的生物学这一非常罕见的,但不同白血病变异与前所未有的轻松。特点与优势分析特性订购方式特点与优势QuantideX qPCR BCR-ABL次要试剂盒(RUO)通过无与伦比的灵敏度和优化的实验室效率提供了高性能。降低复杂性易于数据分析和报告:充分利用了QuantideX ® qPCR的BCR-ABL IS套装的工作流程概念简化实施随附的软件可自动计算BCR-ABL1 / ABL1%比率,无需手动计算优化的工作流程通过以下方式大大减少了宝贵的操作员动手时间:多重设计可在同一反应中扩增并检测融合基因和对照基因单一供应商共同采购和控制质量的全包试剂预混试剂可减少预混液的移液步骤通过高灵敏度的检测方法可靠,可靠地检测 BCR-ABL1次要转录本的质量表现:超灵敏的检测下限(LOD):对数减少4.61(比率为0.0025%)在不影响分析特异性的情况下提高分析灵敏度:结合了空白限度(LOB)以防止误判非白血病低阳性基于铠装RNA®的标准品可提供真正的RNA定量